Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564366 | 0.91 | SMN1; SMN2 (0.60) | LMNAALDH1A1NLRP3HPGDMAPK1 | |
| SCHEMBL7563374 | 0.89 | ALDH1A1 (0.71) | LMNAALDH1A1NLRP3HPGDMAPK1 | |
| SCHEMBL1954916 | 0.88 | LMNA (0.74) | LMNAALDH1A1NLRP3HPGDMAPK1 | |
| SCHEMBL3386794 | 0.86 | SMN1; SMN2 (0.65) | LMNAALDH1A1NLRP3HPGDMAPK1 | |
| SCHEMBL28969409 | 0.84 | MAPK1 (0.69) | LMNAALDH1A1NLRP3HPGDMAPK1 | |
| SCHEMBL9342000 | 0.83 | ALDH1A1 (0.78) | LMNAALDH1A1NLRP3HPGDMAPK1 | |
| SCHEMBL8404940 | 0.81 | SMN1; SMN2 (0.55) | LMNAALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL9463834 | 0.81 | ALDH1A1 (0.60) | LMNAALDH1A1NLRP3HPGDSMN1; SMN2 | |
| SCHEMBL17856292 | 0.81 | NPC1 (0.65) | LMNAALDH1A1NLRP3HPGDMAPK1 | |
| SCHEMBL10489688 | 0.81 | HPGD (0.48) | LMNAALDH1A1NLRP3HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855393-B1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KK (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5922882-A | ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0855393-A1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-07-29 | — | — | EP | disclosed |