Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342000 | 0.95 | ALDH1A1 (0.78) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL7564388 | 0.89 | LMNA (0.60) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL1955909 | 0.86 | NLRP3 (0.80) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL7564366 | 0.86 | SMN1; SMN2 (0.60) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL9721922 | 0.85 | ALDH1A1 (0.61) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL28401182 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL4623246 | 0.83 | MAPT (0.50) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL7916743 | 0.82 | ALDH1A1 (0.81) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL7250114 | 0.82 | ALDH1A1 (0.66) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 | |
| SCHEMBL27570537 | 0.82 | NLRP3 (0.61) | ALDH1A1HPGDNLRP3CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855393-B1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KK (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5922882-A | ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0855393-A1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-07-29 | — | — | EP | disclosed |