Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358286 | 0.82 | SIGMAR1 (0.76) | SIGMAR1LMNATSHRMAPK1L3MBTL1 | |
| SCHEMBL20267190 | 0.79 | SIGMAR1 (0.72) | SIGMAR1PARP1LMNATSHRMAPK1 | |
| SCHEMBL1763270 | 0.78 | SIGMAR1 (0.61) | SIGMAR1PARP1LMNATSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL30444118 | 0.78 | SIGMAR1 (0.70) | SIGMAR1PARP1LMNATSHRMAPK1 | |
| SCHEMBL4709504 | 0.78 | SIGMAR1 (0.65) | SIGMAR1PARP1LMNATSHRMAPK1 | |
| SCHEMBL3584183 | 0.77 | SIGMAR1 (0.69) | SIGMAR1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15986678 | 0.77 | SIGMAR1 (0.59) | SIGMAR1PARP1LMNATSHRMAPK1 | |
| SCHEMBL28393 | 0.77 | SIGMAR1 (1.00) | SIGMAR1TSHRMAPK1USP2CCNC | |
| SCHEMBL894920 | 0.77 | SIGMAR1 (1.00) | SIGMAR1TSHRMAPK1USP2CCNC | |
| SCHEMBL11085975 | 0.76 | ALDH1A1 (0.74) | SIGMAR1PARP1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |