Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 14/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564677 | 0.90 | ACHE (0.51) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL7562945 | 0.84 | KMT2A (0.42) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28251088 | 0.83 | ACHE (0.51) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL28522595 | 0.81 | ACHE (0.56) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL3629794 | 0.80 | ACHE (0.51) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL10580487 | 0.80 | ACHE (0.55) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL31614616 | 0.80 | ACHE (0.55) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL7786502 | 0.78 | ACHE (0.53) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL28614954 | 0.78 | ACHE (0.58) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL1287156 | 0.77 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855393-B1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KK (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5922882-A | ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0855393-A1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-07-29 | — | — | EP | disclosed |