Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 12/20 | 0.42 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005777 | 0.86 | PLA2G7 (0.38) | PLA2G7UPP1 | |
| SCHEMBL7007222 | 0.86 | UPP1 (0.55) | UPP1HPGD | |
| SCHEMBL7007609 | 0.82 | PLA2G7 (0.46) | PLA2G7PNPPKMMAPK10 | |
| SCHEMBL7004509 | 0.81 | PLA2G7 (0.38) | PLA2G7UPP1 | |
| SCHEMBL7009380 | 0.80 | PKM (0.48) | PLA2G7UPP1GAAPKMMAPK10 | |
| SCHEMBL7013517 | 0.79 | PKM (0.45) | PLA2G7PNPGAAHPGDPKM | |
| SCHEMBL7005535 | 0.78 | UPP1 (0.38) | PLA2G7UPP1 | |
| SCHEMBL7013677 | 0.78 | UPP1 (0.57) | UPP1HPGD | |
| SCHEMBL7004030 | 0.77 | PLA2G7 (0.57) | PLA2G7 | |
| SCHEMBL7006845 | 0.76 | PLA2G7 (0.45) | PLA2G7PNPPKMMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020120139-A1 | Pyrimidinone compounds and pharmaceutical compositions containing them | HICKEY DEIRDRE MARY BERNADETTE (GB) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120139-A1 | Pyrimidinone compounds and pharmaceutical compositions containing them | PLA2G7, PLA2G1B, PLA2G4C | PLA2G7 1/4885UPP1 79/4885PNP 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.