Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10043007 | 0.92 | DRD2 (0.71) | DRD2DRD3GRIN2BFYNDRD4 | |
| SCHEMBL11960199 | 0.92 | DRD2 (0.71) | DRD2DRD3GRIN2BFYNDRD4 | |
| SCHEMBL10043005 | 0.92 | DRD2 (0.71) | DRD2DRD3GRIN2BFYNDRD4 | |
| SCHEMBL5142084 | 0.82 | GRIN2B (0.82) | DRD2DRD3GRIN2BFYNSIGMAR1 | |
| SCHEMBL5143976 | 0.81 | DRD2 (0.86) | DRD2DRD3GRIN2BDRD4SIGMAR1 | |
| SCHEMBL11075369 | 0.79 | DRD2 (0.70) | DRD2DRD3GRIN2BDRD4SIGMAR1 | |
| SCHEMBL10043003 | 0.78 | DRD2 (0.71) | DRD2DRD3GRIN2BFYNDRD4 | |
| SCHEMBL10043001 | 0.78 | DRD2 (0.71) | DRD2DRD3GRIN2BFYNDRD4 | |
| SCHEMBL11960195 | 0.78 | DRD2 (0.71) | DRD2DRD3GRIN2BFYNDRD4 | |
| Hydrochloric Acid SCHEMBL5144066 | 0.77 | KMT2A (0.56) | DRD2DRD3DRD4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391915-B2 | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| US-20020006956-A1 | Propanolamine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-0976720-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006956-A1 | Propanolamine derivatives | PNLIP, ADRB1, FABP2 | DRD2 115/4885DRD3 103/4885GRIN2B 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.