Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 12/20 | 0.43 |
| ▸ | PLG | P00747 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | PLAT | P00750 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564461 | 0.89 | PLAU (0.42) | PLAUPLGPRSS1F2KLK1 | |
| SCHEMBL7564845 | 0.84 | FTO (0.43) | PLAUPLGPRSS1F2KLK1 | |
| SCHEMBL7564449 | 0.81 | FTO (0.45) | PLAUPLGPRSS1F2KLK1 | |
| SCHEMBL7562999 | 0.81 | PLAU (0.46) | PLAUPLGPRSS1F2KLK1 | |
| SCHEMBL7563375 | 0.78 | PLAU (0.43) | PLAUPLGPRSS1F2KLK1 | |
| SCHEMBL7561463 | 0.74 | PRSS1 (0.69) | PRSS1F2KLK1FTOKLKB1 | |
| SCHEMBL7564455 | 0.72 | KDM4E (0.51) | PLAUPLGPRSS1F2KLK1 | |
| SCHEMBL7326867 | 0.72 | KDM4E (0.43) | PLAUPLGPRSS1F2KLK1 | |
| Hydrochloric Acid SCHEMBL7562340 | 0.72 | FTO (0.46) | PLAUPLGPRSS1F2KLK1 | |
| SCHEMBL7562225 | 0.72 | FTO (0.46) | PLAUPLGPRSS1F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802179-B1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO LTD (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-5885990-A | FIBRINOLYSIS PROMOTING ACTION; THROMBOLYSIS ACTION | TORII PHARMACEUTICAL CO., LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0802179-A1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO., LTD. (JP) | 1997-10-22 | — | — | EP | disclosed |