Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | NQO2 | P16083 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573459 | 1.00 | ALDH1A1 (0.65) | ALDH1A1POLBKMT2ARAB9AMEN1 | |
| SCHEMBL5886295 | 0.85 | KDM4E (0.54) | ALDH1A1POLBKMT2ARAB9AMEN1 | |
| SCHEMBL5886371 | 0.84 | KDM4E (0.52) | ALDH1A1POLBKMT2ARAB9AMEN1 | |
| SCHEMBL7570741 | 0.81 | ALDH1A1 (0.71) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL2288888 | 0.81 | ALDH1A1 (0.71) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL7568147 | 0.81 | KDM4E (0.48) | ALDH1A1POLBKMT2ARAB9AMEN1 | |
| SCHEMBL7566734 | 0.81 | KDM4E (0.51) | ALDH1A1POLBKMT2ARAB9AMEN1 | |
| Phenazine-1-Carboxylic Acid SCHEMBL27752237 | 0.80 | ALDH1A1 (0.93) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| Phenazine-1-Carboxylic Acid SCHEMBL122864 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| Phenazine-1-Carboxylic Acid SCHEMBL27884214 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-08 | — | — | US | disclosed |
| EP-3086791-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | University of Florida Research Foundation, Inc. (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2015100331-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-07-02 | — | — | WO | disclosed |
| WO-2015100331-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-07-02 | — | — | WO | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | ROS1, NOX4, NOX5 | ALDH1A1 1136/4885POLB 938/4885KMT2A 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.