Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288888 | 1.00 | ALDH1A1 (0.71) | ALDH1A1NQO2MEN1KMT2AMAPT | |
| Phenazine-1-Carboxylic Acid SCHEMBL27752237 | 0.84 | ALDH1A1 (0.93) | ALDH1A1NQO2MEN1KMT2AMAPT | |
| Phenazine-1-Carboxylic Acid SCHEMBL28160016 | 0.84 | ALDH1A1 (1.00) | ALDH1A1NQO2MEN1KMT2AMAPT | |
| Phenazine-1-Carboxylic Acid SCHEMBL29370801 | 0.84 | ALDH1A1 (1.00) | ALDH1A1NQO2MEN1KMT2AMAPT | |
| Phenazine-1-Carboxylic Acid SCHEMBL122864 | 0.84 | ALDH1A1 (1.00) | ALDH1A1NQO2MEN1KMT2AMAPT | |
| Phenazine-1-Carboxylic Acid SCHEMBL27884214 | 0.84 | ALDH1A1 (1.00) | ALDH1A1NQO2MEN1KMT2AMAPT | |
| SCHEMBL5696607 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL29337447 | 0.83 | ALDH1A1 (0.73) | ALDH1A1NQO2MEN1KMT2AMAPT | |
| SCHEMBL8187609 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL29337448 | 0.83 | ALDH1A1 (0.73) | ALDH1A1NQO2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-08 | — | — | US | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | ROS1, NOX4, NOX5 | ALDH1A1 1136/4885NQO2 349/4885MEN1 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.