Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.47 |
| ▸ | GRM8 | O00222 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567942 | 0.84 | CYP1A2 (0.48) | CYP1A2TSHRGRM4GRM8ALDH1A1 | |
| SCHEMBL12278883 | 0.79 | MAPT (0.37) | GRM4GRM8MEN1KMT2A | |
| SCHEMBL17094769 | 0.77 | CYP1A2 (0.43) | CYP1A2TSHRALDH1A1 | |
| SCHEMBL7877336 | 0.76 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1 | |
| SCHEMBL15346298 | 0.76 | GRM4 (0.41) | CYP1A2TSHRGRM4GRM8ALDH1A1 | |
| SCHEMBL15346295 | 0.76 | CYP1A2 (0.41) | CYP1A2TSHRGRM4GRM8ALDH1A1 | |
| SCHEMBL14735892 | 0.75 | CYP1A2 (0.61) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL14733944 | 0.74 | ALDH1A1 (0.55) | CYP1A2TSHRALDH1A1 | |
| SCHEMBL29966092 | 0.74 | ALDH1A1 (0.46) | CYP1A2TSHRGRM4GRM8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28879328 | 0.73 | ALDH1A1 (0.45) | CYP1A2TSHRGRM4GRM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074176-A1 | METHODS FOR MODULATING NEURAL ACTIVITY IN THE RETINA | UNIVERSITY OF WASHINGTON (US) | 2002-09-26 | — | — | WO | claimed |