SCHEMBL7565093

SCHEMBL7565093

CCCOc1cc([Se]C#C/C(C)=C/C(=O)OCC)cc2c1C(C)(C)CCC2(C)C

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RXRA P19793 8/20 0.40
RARA P10276 2/20 0.40
RARB P10826 2/20 0.40
RARG P13631 2/20 0.40
RXRB P28702 2/20 0.40
RXRG P48443 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6473357 1.00 RXRA (0.40) RXRARARARARBRARGRXRB
SCHEMBL6478308 0.90 RXRA (0.33) RXRARARARARBRARGRXRB
SCHEMBL7558406 0.90 RXRA (0.33) RXRARARARARBRARGRXRB
SCHEMBL6476755 0.90 RXRA (0.48) RXRARARARARBRARGRXRB
SCHEMBL7561527 0.90 RXRA (0.48) RXRARARARARBRARGRXRB
SCHEMBL7560404 0.88 RARA (0.34) RXRARARARARBRARGRXRB
SCHEMBL6472712 0.88 RARA (0.34) RXRARARARARBRARGRXRB
SCHEMBL7558629 0.84 RXRA (0.46) RXRARARARARBRARGRXRB
SCHEMBL6473196 0.84 RXRA (0.46) RXRARARARARBRARGRXRB
SCHEMBL7558455 0.80 RARB (0.38) RXRARARARARBRARGRXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986537-B1 NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME GALDERMA RES & DEV (FR) 2002-08-07 EP claimed