Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069192 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1LMNATSHR | |
| SCHEMBL28112414 | 0.80 | — | — | |
| SCHEMBL667439 | 0.71 | — | — | |
| SCHEMBL13309991 | 0.68 | — | — | |
| SCHEMBL7321 | 0.68 | — | — | |
| SCHEMBL11841381 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL5012159 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL3855161 | 0.66 | CA12 (0.38) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL13434243 | 0.66 | SMN1; SMN2 (0.39) | ALDH1A1LMNATSHRCA1CA9 | |
| SCHEMBL16607618 | 0.66 | SMN1; SMN2 (0.39) | ALDH1A1LMNATSHRCA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137687-B2 | Implantable medical device having a coating of a biocompatible polylactone from N-substituted 4-aza-caprolactone | MEDTRONIC VASCULAR, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-8137687-B2 | Implantable medical device having a coating of a biocompatible polylactone from N-substituted 4-aza-caprolactone | MEDTRONIC VASCULAR, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1984036-B1 | 4-AZA-CAPROLACTONE-BASED POLYMERIC COMPOSITIONS USEFUL FOR THE MANUFACTURE OF BIODEGRADABLE MEDICAL DEVICES AND AS MEDICAL DEVICE COATINGS | MEDTRONIC VASCULAR INC (US) | 2010-06-30 | — | — | EP | disclosed |
| US-20080233169-A1 | 4-Aza-Caprolactone-Based Polymeric Compositions Useful for the Manufacture of Biodegradable Medical Devices and as Medical Device Coatings | MEDTRONIC VASULAR, INC. (US) | 2008-09-25 | — | — | US | disclosed |
| US-20080233169-A1 | 4-Aza-Caprolactone-Based Polymeric Compositions Useful for the Manufacture of Biodegradable Medical Devices and as Medical Device Coatings | MEDTRONIC VASULAR, INC. (US) | 2008-09-25 | — | — | US | disclosed |
| WO-2007024481-A2 | 4-AZA-CAPROLACTONE-BASED POLYMERIC COMPOSITIONS USEFUL FOR THE MANUFACTURE OF BIODEGRADABLE MEDICAL DEVICES AND AS MEDICAL DEVICE COATINGS | MEDTRONIC VASCULAR, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233169-A1 | 4-Aza-Caprolactone-Based Polymeric Compositions Useful for the Manufacture of Biodegradable Medical Devices and as Medical Device Coatings | CAD, ACMSD, TET3 | ALDH1A1 3945/4885LMNA 623/4885TP53 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.