Paraben

Paraben

SCHEMBL7565100

CC(O)Oc1ccccc1.O=C(O)c1ccc(O)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA12 O43570 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
CA3 P07451 1/20 0.53
TYR P14679 1/20 0.53
DRD1 P21728 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
SRD5A2 P31213 5/20 0.49
PKM P14618 1/20 0.46
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL2230871 0.90 KMT2A (0.58) KMT2ACA1CA2RXRARXRB
4-Hydroxyacetophenone SCHEMBL28253051 0.89 HSD17B1 (0.50) KMT2ACA1CA2CA12CA7
Methylparaben SCHEMBL165373 0.86 CA1 (0.61) KMT2ACA1CA2CA12CA7
SCHEMBL79929 0.86 KMT2A (0.74) KMT2ACA1CA2RXRARXRB
SCHEMBL10867743 0.86 KMT2A (0.74) KMT2ACA1CA2RXRARXRB
Isopropyl 4-Hydroxybenzoate SCHEMBL4729205 0.84 CA12 (0.68) KMT2ACA1CA2CA12CA7
Phenol SCHEMBL15568698 0.84 TDP1 (0.48) KMT2ACA1CA2CA12CA9
SCHEMBL28842646 0.81 ADRB2 (0.52) KMT2ACA1CA2CA12CA7
Hydroquinone SCHEMBL8984334 0.81 KMT2A (0.85) KMT2ACA1CA2CA12CA7
SCHEMBL8429335 0.81 KMT2A (0.67) KMT2ACA1CA2RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929182-A Hair conditioner compositions with preservative system comprising sodium benzoate and glycols and/or glycerides 宝洁公司 2022-08-19 CN disclosed
EP-1201220-A1 Cosmetic or pharmaceutical compositions containing thermostabilising microcapsules L'OREAL (FR) 2002-05-02 EP disclosed
US-5302380-A Containing atactic polypropylene; good adhesion REVLON CONSUMER PRODUCTS CORPORATION (US) 1994-04-12 US disclosed