Isopropyl 4-Hydroxybenzoate

Isopropyl 4-Hydroxybenzoate

SCHEMBL4729205

CC(C)OC(=O)c1ccc(O)cc1.CC(O)Oc1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.68
CA1 P00915 7/20 0.68
CA2 P00918 7/20 0.68
CA7 P43166 7/20 0.68
CA9 Q16790 7/20 0.68
CA14 Q9ULX7 7/20 0.68
PDCD1 Q15116 1/20 0.58
CD274 Q9NZQ7 1/20 0.58
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
HTT P42858 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylparaben SCHEMBL165373 0.87 CA1 (0.61) CA12CA1CA2CA7CA9
Paraben SCHEMBL7565100 0.84 KMT2A (0.56) CA12CA1CA2CA7CA9
4-Hydroxyacetophenone SCHEMBL28253051 0.83 HSD17B1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL160689 0.83 CA12 (0.59) CA12CA1CA2CA7CA9
Butylparaben SCHEMBL27700689 0.82 TSHR (0.54) CA12CA1CA2CA7CA9
Isopropyl 4-Hydroxybenzoate SCHEMBL34494 0.82 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL28842646 0.82 ADRB2 (0.52) CA12CA1CA2CA7CA9
SCHEMBL28808715 0.81 LMNA (0.47) CA12CA1CA2CA7CA9
Propylparaben SCHEMBL830283 0.81 ALDH1A1 (0.66) CA12CA1CA2CA7CA9
Isopropyl 4-Hydroxybenzoate SCHEMBL1712159 0.81 CA12 (0.96) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100567406-C Aluminum effect pigment blends ENGELHARD CORP (US) 2009-12-09 CN disclosed
WO-2008034178-A1 TOPICAL DEPILATING COMPOSITION IEMMA SALVATORE (AU) 2008-03-27 WO disclosed
US-6649150-B2 Extract containing flavonoids EM INDUSTRIES 2003-11-18 US disclosed