Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566818 | 0.93 | KMT2A (0.53) | ALDH1A1ALOX15KDM4EATMKMT2A | |
| SCHEMBL8106737 | 0.93 | KMT2A (0.53) | ALDH1A1ALOX15KDM4EATMKMT2A | |
| SCHEMBL7589850 | 0.93 | KMT2A (0.53) | ALDH1A1ALOX15KDM4EATMKMT2A | |
| SCHEMBL8103041 | 0.93 | KMT2A (0.53) | ALDH1A1ALOX15KDM4EATMKMT2A | |
| SCHEMBL9323493 | 0.84 | ALOX15 (0.49) | ALDH1A1ALOX15KDM4EATMPOLB | |
| SCHEMBL7561749 | 0.81 | CYP2D6 (0.47) | TSHRALDH1A1ALOX15KDM4EATM | |
| SCHEMBL22558000 | 0.80 | KMT2A (0.38) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL3709138 | 0.79 | ALDH1A1 (0.47) | TSHRALDH1A1ALOX15CYP3A4 | |
| SCHEMBL5437325 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL7561321 | 0.78 | ALOX15 (0.42) | TSHRALDH1A1ALOX15KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |