Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106652 | 0.93 | ALOX15 (0.51) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL8093235 | 0.93 | ALOX15 (0.51) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL7560775 | 0.93 | ALOX15 (0.51) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL7582869 | 0.93 | ALOX15 (0.51) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL22558163 | 0.83 | ALOX15 (0.40) | CYP2D6CYP2C19ALDH1A1ALOX15TSHR | |
| SCHEMBL7561321 | 0.82 | ALOX15 (0.42) | ALDH1A1ALOX15TSHRKDM4EATM | |
| SCHEMBL3771224 | 0.81 | FAAH (0.50) | CYP2D6CYP2C19ALDH1A1ALOX15GLO1 | |
| SCHEMBL7565263 | 0.81 | TSHR (0.45) | ALDH1A1ALOX15TSHRKDM4EATM | |
| SCHEMBL410005 | 0.81 | ALDH1A1 (0.42) | CYP2D6CYP2C19ALDH1A1ALOX15TSHR | |
| SCHEMBL3756251 | 0.81 | ALDH1A1 (0.42) | CYP2D6CYP2C19ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |