Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326868 | 0.91 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL88855 | 0.74 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL2469938 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL2734098 | 0.73 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL7186170 | 0.71 | TP53 (0.35) | ALDH1A1 | |
| SCHEMBL5693416 | 0.70 | TSHR (0.39) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9003450 | 0.70 | LMNA (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL11346122 | 0.68 | TP53 (0.32) | — | |
| SCHEMBL5668391 | 0.67 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL5906917 | 0.66 | ALDH1A1 (0.39) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937043-B1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2002-03-06 | — | — | EP | claimed |
| EP-0937043-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-08-25 | — | — | EP | claimed |
| WO-1998024765-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-11 | — | — | WO | claimed |
| EP-0937043-B1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2002-03-06 | — | — | EP | disclosed |
| US-6232319-B1 | TREATMENT OF MEMORY DEFECTS ASSOCIATED WITH CEREBRAL AGING AND WITH NEURODEGENERATIVE DISEASES INCLUDING ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, PICK'S DISEASE, KORSAKOFF'S DISEASE AND FRONTAL AND SUBCOTICAL DEMENTIAS | ADIR ET COMPAGNIE (FR) | 2001-05-15 | — | — | US | disclosed |
| US-6184180-B1 | COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE | MITSUBISHI PAPER MILLS LIMITED (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0937043-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998024765-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-11 | — | — | WO | disclosed |
| US-5500453-A | INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |