SCHEMBL9003450

SCHEMBL9003450

C=CC[S+](c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
CYP2A6 P11509 1/20 0.36
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.31
IDO1 P14902 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MMP9 P14780 1/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2326868 0.76 ALDH1A1 (0.36) ALDH1A1CYP2C19
SCHEMBL9003372 0.72 TSHR (0.38) LMNAALDH1A1HPGDHSD17B10MEN1
SCHEMBL11876166 0.70 NQO1 (0.52) ALDH1A1NPC1MAPTRAB9ARELA
SCHEMBL7565374 0.70 ALDH1A1 (0.31) ALDH1A1L3MBTL1
SCHEMBL5835270 0.65 LMNA (0.38) LMNACYP2A6ALDH1A1HSD17B10IDO1
SCHEMBL1427989 0.64 ALDH1A1 (0.52) LMNACYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL158291 0.63 LMNA (0.57) LMNACYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL9003539 0.62 SIGMAR1 (0.44) ALDH1A1HPGDHSD17B10L3MBTL1MEN1
Bromide SCHEMBL547810 0.61 LMNA (0.53) LMNACYP2A6ALDH1A1HPGDHSD17B10
Water SCHEMBL8070851 0.61 LMNA (0.53) LMNACYP2A6ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500453-A INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-19 US disclosed