Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16018989 | 0.87 | ABCB1 (0.68) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL10447265 | 0.85 | NPC1 (0.52) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL95495 | 0.81 | MAPT (0.59) | ABCB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL12301149 | 0.81 | ABCB1 (0.60) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL29227204 | 0.80 | ALDH1A1 (0.53) | NPC1RAB9AHTR1AAPPMAOB | |
| SCHEMBL12358221 | 0.79 | NPC1 (0.65) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL11083926 | 0.79 | APP (0.65) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL30145233 | 0.79 | ABCB1 (0.59) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL7914167 | 0.79 | ABCB1 (0.59) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL4518756 | 0.79 | APP (0.60) | ABCB1NPC1RAB9AHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741741-B1 | MODIFIED OLIGONUCLEOTIDES | NOVARTIS AG (CH) | 2002-08-28 | — | — | EP | disclosed |
| US-6066447-A | INCLUDING NUCLEOSIDE DIMERS WITH MODIFIED BACKBONES; FOR VIRICIDES AND ANTISENSE AGENTS | NOVARTIS CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| WO-1998000434-A1 | MODIFIED OLIGONUCLEOTIDES | NOVARTIS AG (CH) | 1998-01-08 | — | — | WO | disclosed |
| EP-0741741-A1 | MODIFIED OLIGONUCLEOTIDES | Novartis AG (CH) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020597-A1 | MODIFIED OLIGONUCLEOTIDES | CIBA-GEIGY AG (CH) | 1995-08-03 | — | — | WO | disclosed |
| EP-0164850-B1 | A NOVEL PROCESS FOR THE PREPARATION OF OXAZOLINES | ELI LILLY AND COMPANY (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4587053-A | Preparation of oxazolines | ELI LILLY AND COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0164850-A1 | A novel process for the preparation of oxazolines | ELI LILLY AND COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4414210-A | 2-Hydroxyarylethyltriazole fungicides | ROHM AND HAAS COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4413003-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| US-4271296-A | CEPHALOSPORINS AND DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4271295-A | HALOGENATION STEP | SHIONOGI & CO., LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4220766-A | FROM PENICILLINS | SHIONOGI & CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |
| US-4183855-A | INTERMEDIATES FOR PREPARATION OF THE BACTERICIDE, 1-OXADETHIA-CEPHALOSPORIN | SHIONOGI & CO., LTD. (JP) | 1980-01-15 | — | — | US | disclosed |