Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 6/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21380701 | 0.88 | MEN1 (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL29227204 | 0.86 | ALDH1A1 (0.53) | MAPTL3MBTL1HTR1ASLC6A2SLC6A3 | |
| SCHEMBL6672651 | 0.84 | TSHR (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL27515339 | 0.84 | MAPT (0.56) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL339812 | 0.84 | MAPT (0.71) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL27438190 | 0.83 | L3MBTL1 (0.55) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL27476393 | 0.83 | MAPT (0.55) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL7446179 | 0.83 | MAPT (0.76) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| Formaldehyde SCHEMBL27831678 | 0.82 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL7565429 | 0.81 | ABCB1 (0.59) | HTR1ALTA4HADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 833 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177250-A1 | NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 숙명여자대학교산학협력단 | 2023-09-21 | — | — | WO | claimed |
| WO-2023177249-A1 | NOVEL BINARY HISTONE DEACETYLASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 숙명여자대학교산학협력단 | 2023-09-21 | — | — | WO | claimed |
| CN-113874375-A | Cyclic amide compounds and methods thereof for the treatment of rabies | 株式会社大分大学先端医学研究所 | 2021-12-31 | — | — | CN | claimed |
| WO-2020246503-A1 | CYCLIC AMIDE COMPOUNDS FOR RABIES TREATMENT AND METHOD THEREOF | 株式会社大分大学先端医学研究所 | 2020-12-10 | — | — | WO | claimed |
| CN-107924124-A | Negative photoresist composition for I-line with excellent etching resistance | 荣昌化学制品株式会社 | 2018-04-17 | — | — | CN | claimed |
| WO-2017093157-A1 | PIPERIDINE, PYRROLIDINE AND 2-OXO-1,3-OXAZINANE DERIVATIVES AS INHIBITORS OF BACTERIAL EFFLUX-PUMPS FOR THE TREATMENT OF MICROBIAL INFECTIONS | BASILEA PHARMACEUTICA AG (CH) | 2017-06-08 | — | — | WO | claimed |
| EP-2880020-A1 | ENZYME-ACTIVATING COMPOUNDS AND COMPOSITIONS | The Board of Trustees of the University of Illinois (US) | 2015-06-10 | — | — | EP | claimed |
| WO-2014022858-A1 | ENZYME-ACTIVATING COMPOUNDS AND COMPOSITIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-02-06 | — | — | WO | claimed |
| CN-103339116-A | Substituted n-valeramide compound, preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-10-02 | — | — | CN | claimed |
| US-8466295-B2 | Thiophene derivatives as factor XIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-06-18 | — | — | US | claimed |
| US-4599361-A | ANTIARTHRITIC | G. D. SEARLE & CO. (US) | 1986-07-08 | — | — | US | claimed |
| EP-0185380-A2 | Thiol based collagenase inhibitors | G.D. Searle & Co. (US) | 1986-06-25 | — | — | EP | claimed |
| US-4595700-A | Thiol based collagenase inhibitors | G. D. SEARLE & CO. (US) | 1986-06-17 | — | — | US | claimed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | claimed |
| US-4436726-A | TREATMENT OF IMMUNE DEFICIENCY DISEASES AND THROMBOSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | claimed |
| EP-0054435-B1 | N-ACYL PEPTIDE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-25 | — | — | EP | claimed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | claimed |
| EP-0054435-A1 | N-acyl peptide compounds, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-23 | — | — | EP | claimed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | claimed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |