Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355645 | 0.89 | POLB (0.55) | ALDH1A1MAPTGAAHTTPOLB | |
| SCHEMBL9779970 | 0.86 | GAA (0.53) | ALDH1A1HPGDMAPTGAAKMT2A | |
| SCHEMBL2542902 | 0.85 | EGFR (0.56) | ALDH1A1HPGDMAPTGAAEGFR | |
| SCHEMBL8168563 | 0.84 | MAPT (0.53) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL29860111 | 0.84 | MAPT (0.53) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL6908097 | 0.83 | SYK (0.61) | ALDH1A1MAPTGAAEGFRPOLB | |
| SCHEMBL2535177 | 0.83 | EGFR (0.54) | ALDH1A1HPGDMAPTGAAEGFR | |
| SCHEMBL5287728 | 0.82 | MAPT (0.54) | ALDH1A1HPGDMAPTGAAEGFR | |
| SCHEMBL20839664 | 0.82 | SYK (0.49) | ALDH1A1MAPTHTTPOLBSMN1; SMN2 | |
| SCHEMBL8819532 | 0.82 | POLB (0.52) | MAPTEGFRKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118390075-A | Synthesis method of glycine ester compound | 中国计量大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-115521354-A | Method for synthesizing polypeptide compound through carbon-hydrogen amination reaction catalyzed by visible light oxidation reduction | 深圳市图微安创科技开发有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-1441673-A | 4,5-dihydro-thiazo-2-ylamine derivatives and their use as NO-synthase inhibitors | AVENTIS PHARMA SA (FR) | 2003-09-10 | — | — | CN | disclosed |
| US-6420566-B2 | NITRIC OXIDE SYNTHASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2002-07-16 | — | — | US | disclosed |
| US-20020019427-A1 | Pharmaceutical compositions containing a 4, 5-dihydro-1, 3-thiazol-2-ylamine derivative, novel derivatives and preparation thereof | AVENTIS PHARMA S.A. (FR) | 2002-02-14 | — | — | US | disclosed |
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019427-A1 | Pharmaceutical compositions containing a 4, 5-dihydro-1, 3-thiazol-2-ylamine derivative, novel derivatives and preparation thereof | ALK, QDPR, CYP3A7 | ALDH1A1 22/4885HPGD 560/4885MAPT 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.