Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735809 | 0.84 | NPC1 (0.43) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL9223355 | 0.80 | ALDH1A1 (0.43) | MAPTSMN1; SMN2L3MBTL1HPGDPIN1 | |
| SCHEMBL10831459 | 0.80 | EPAS1 (0.46) | HSPB1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL3208120 | 0.79 | ALDH1A1 (0.52) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL15861931 | 0.78 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL27756639 | 0.78 | NPC1 (0.40) | MAPTNPC1RAB9AHPGDMEN1 | |
| SCHEMBL1997338 | 0.77 | TLR4 (0.46) | HSPB1MAPTSMN1; SMN2L3MBTL1NPSR1 | |
| SCHEMBL16590518 | 0.74 | TDP1 (0.57) | MAPTSMN1; SMN2L3MBTL1HPGDMEN1 | |
| SCHEMBL21684753 | 0.74 | HSPB1 (0.64) | HSPB1MAPTSMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL17599647 | 0.73 | HTR1A (0.40) | MEN1KMT2ARHEBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002071057-A1 | IONOPHORE-BASED SENSORS | THERMO ORION INC. (US) | 2002-09-12 | — | — | WO | disclosed |