Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570358 | 0.89 | MEN1 (0.52) | KMT2AMEN1LMNAKDM4EGMNN | |
| Hydrochloric Acid SCHEMBL7566243 | 0.89 | MEN1 (0.51) | KMT2AMEN1LMNAKDM4EGMNN | |
| Hydrochloric Acid SCHEMBL5146523 | 0.87 | DRD2 (0.55) | KMT2AMEN1LMNAKDM4EGMNN | |
| Hydrochloric Acid SCHEMBL5144066 | 0.83 | KMT2A (0.56) | KMT2AMEN1LMNAKDM4EGMNN | |
| SCHEMBL7569470 | 0.82 | ADRB3 (0.58) | KMT2AMEN1LMNAKDM4EGMNN | |
| SCHEMBL7570735 | 0.82 | ADRB3 (0.54) | KMT2AMEN1LMNAKDM4EGMNN | |
| SCHEMBL7564734 | 0.82 | ADRB3 (0.58) | KMT2AMEN1LMNAKDM4EGMNN | |
| SCHEMBL7566211 | 0.82 | ADRB3 (0.58) | KMT2AMEN1LMNAKDM4EGMNN | |
| SCHEMBL7563492 | 0.82 | ADRB3 (0.58) | KMT2AMEN1LMNAKDM4EGMNN | |
| Hydrochloric Acid SCHEMBL5144170 | 0.81 | KMT2A (0.63) | KMT2AMEN1LMNAKDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391915-B2 | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| US-20020006956-A1 | Propanolamine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-0976720-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006956-A1 | Propanolamine derivatives | PNLIP, ADRB1, FABP2 | KMT2A 3913/4885MEN1 1395/4885LMNA 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.