SCHEMBL9064159

SCHEMBL9064159

CCOC(=O)NC(=S)Nc1cccc(C(F)(F)F)c1

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.65
ALOX12 P18054 4/20 0.65
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
NPSR1 Q6W5P4 3/20 0.65
POLB P06746 1/20 0.65
KDM4E B2RXH2 1/20 0.60
XBP1 P17861 1/20 0.60
LMNA P02545 3/20 0.60
MAPT P10636 6/20 0.59
CCR6 P51684 2/20 0.59
GAA P10253 7/20 0.59
NPY1R P25929 1/20 0.59
TDP1 Q9NUW8 3/20 0.58
HTT P42858 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
IDO1 P14902 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565660 0.87 SMN1; SMN2 (0.62) ALDH1A1MEN1KMT2ANPSR1POLB
SCHEMBL23727485 0.83 ALDH1A1 (0.62) ALDH1A1ALOX12MEN1KMT2APOLB
SCHEMBL23727571 0.81 TRPV1 (0.56) ALDH1A1MEN1KMT2AGAATDP1
SCHEMBL1011218 0.80 ALDH1A1 (0.64) ALDH1A1ALOX12MEN1KMT2ANPSR1
SCHEMBL23727753 0.80 MTNR1B (0.63) ALDH1A1MEN1KMT2APOLBMAPT
SCHEMBL596433 0.79 ALDH1A1 (0.60) ALDH1A1ALOX12MEN1KMT2ANPSR1
SCHEMBL31748813 0.78 ALDH1A1 (0.67) ALDH1A1ALOX12MEN1KMT2ANPSR1
SCHEMBL333191 0.78 SMN1; SMN2 (0.65) ALDH1A1MEN1KMT2ANPSR1XBP1
SCHEMBL10688602 0.78 SMN1; SMN2 (0.57) ALDH1A1MEN1KMT2ANPSR1POLB
SCHEMBL7175227 0.78 MAPT (0.86) ALDH1A1MEN1KMT2ANPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508415-A HAVING STRONG HERBICIDAL POTENCY, NOTICEABLE SELECTIVITY BETWEEN CROP PLANTS AND WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-16 US disclosed
US-5426188-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-20 US disclosed
EP-0446802-B1 Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 1995-06-07 EP disclosed
US-5244863-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-09-14 US disclosed
EP-0446802-A1 Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-18 EP disclosed