SCHEMBL7565723

SCHEMBL7565723

O=C1OCC=C1Cc1cccc(-c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.44
NAAA Q02083 1/20 0.44
IDH1 O75874 1/20 0.42
HRH3 Q9Y5N1 1/20 0.40
AGXT P21549 1/20 0.40
PTPN5 P54829 1/20 0.40
ACMSD Q8TDX5 1/20 0.39
AOC3 Q16853 3/20 0.37
GGPS1 O95749 2/20 0.37
GPR84 Q9NQS5 1/20 0.37
PDE10A Q9Y233 1/20 0.36
HTR1A P08908 1/20 0.36
DRD2 P14416 1/20 0.36
BCL2 P10415 1/20 0.36
KDM1A O60341 1/20 0.35
MAOA P21397 1/20 0.35
DAO P14920 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP12 P39900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7359765 0.76 CTRC (0.46) NAAA
SCHEMBL2843937 0.73 AGXT (0.59) IDH1HRH3AGXTPTPN5ACMSD
SCHEMBL9625135 0.71 CALM1 (0.60) IDH1HRH3AGXTPTPN5ACMSD
SCHEMBL31498881 0.71 CALM1 (0.60) IDH1HRH3AGXTPTPN5ACMSD
SCHEMBL31498880 0.71 CALM1 (0.60) IDH1HRH3AGXTPTPN5ACMSD
SCHEMBL29040199 0.69 ACMSD (0.61) IDH1HRH3AGXTPTPN5ACMSD
SCHEMBL28573022 0.66 ACMSD (0.53) IDH1HRH3AGXTPTPN5ACMSD
SCHEMBL1262278 0.66 AGXT (0.55) HRH3AGXTPTPN5AOC3GGPS1
SCHEMBL979621 0.64 CFTR (0.43) DRD2MAOA
SCHEMBL22698824 0.64 CYP3A4 (0.60) HRH3AGXTPTPN5ACMSDGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1192213-A1 STABILIZATION OF PLASTICS AND ARTICLES PRODUCED OR COATED THEREWITH Clariant Finance (BVI) Limited (VG) 2002-04-03 EP disclosed
WO-2000077084-A1 STABILIZATION OF PLASTICS AND ARTICLES PRODUCED OR COATED THEREWITH CLARIANT FINANCE (BVI) LIMITED (VG) 2000-12-21 WO disclosed