SCHEMBL756575

SCHEMBL756575

COc1cc(CO)c(OC)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.52
PDE4B Q07343 1/20 0.52
PDE4C Q08493 1/20 0.52
PDE4D Q08499 1/20 0.52
HMGCR P04035 2/20 0.52
CYP3A4 P08684 5/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 2/20 0.50
RECQL P46063 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TP53 P04637 1/20 0.50
MAOB P27338 1/20 0.43
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
NFKB1 P19838 1/20 0.42
MMP8 P22894 1/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16156475 0.89 PDE4A (0.62) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL10728345 0.87 PDE4A (0.52) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL9818760 0.87 PDE4A (0.52) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL14283785 0.87 PDE4A (0.52) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL95746 0.84 PDE4A (0.64) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL26110762 0.83 HMGCR (0.57) HMGCRCYP3A4KDM4EMAPTALDH1A1
SCHEMBL14307320 0.82 HMGCR (0.47) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL18475740 0.82 TRPV1 (0.49) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL1743710 0.82 PDE4A (0.47) PDE4APDE4BPDE4CPDE4DHMGCR
SCHEMBL27557583 0.81 HMGCR (0.50) HMGCRCYP3A4KDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4382588-A1 ADDITIVES FOR IMPROVING THERMAL STABILITY OF FUELS BASF SE (DE) 2024-06-12 EP claimed
CN-117203185-B Diisocyanate stabilizer, use thereof and diisocyanate composition 巴斯夫欧洲公司 2026-05-12 CN disclosed
US-20260002013-A1 SUSTAINABLE ANTIOXIDANT COMPOSITION, USE THEREOF AND POLYMER COMPOSITION COMPRISING THE SAME BASF SE (DE) 2026-01-01 US disclosed
EP-4419580-B1 METHOD FOR PROMOTING HYDROSILYLATION REACTION TO PREPARE ESTER-FUNCTIONAL SILOXANE OLIGOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-27 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions DOW SILICONES CORPORATION (US) 2025-08-05 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
EP-4172165-B1 PREPARATION OF MULTIFUNCTIONAL ORGANOSILICON COMPOUNDS DOW SILICONES CORP (US) 2025-07-23 EP disclosed
US-20250136625-A1 PROCESS FOR THE PREPARATION OF ORGANIC SILICON COMPOUNDS BASF SE (DE) 2025-05-01 US disclosed
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS DOW SILICONES CORP (US) 2025-05-01 US disclosed
WO-2003104302-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED TRIMETHYLOLPROPANE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003104301-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED GLYCERINE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003104299-A1 METHOD FOR THE PRODUCTION OF ESTERS OF POLYALCOHOLS BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003104300-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED TRIMETHYLOLPROPANE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003099757-A1 STABILISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS COMPRISING HYDROXYLAMINE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2003-12-04 WO disclosed
EP-1345882-A2 METHOD FOR PRODUCING (METH)ACRYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2003-09-24 EP disclosed
WO-2003057657-A1 METHOD FOR PRODUCING ACRYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2003-07-17 WO disclosed
US-20030060654-A1 Preparation of polymerizable compounds BASF AKIENGESELLSCHAFT (DE) 2003-03-27 US disclosed
WO-2002051786-A2 METHOD FOR PRODUCING (METH)ACRYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2002-07-04 WO disclosed
US-3983160-A Process for the preparation of hydroxyphenylacetonitriles BAYER AKTIENGESELLSCHAFT (DT) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions MSR1, OXSR1, RIOX2 PDE4A 4877/4885PDE4B 4875/4885PDE4C 4883/4885
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS VCL, FANCF, MMS19 PDE4A 4204/4885PDE4B 4485/4885PDE4C 4245/4885
US-20260002013-A1 SUSTAINABLE ANTIOXIDANT COMPOSITION, USE THEREOF AND POLYMER COMPOSITION COMPRISING THE SAME GPX4, TTPA, GPX1 PDE4A 4461/4885PDE4B 4227/4885PDE4C 4069/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 PDE4A 4586/4885PDE4B 4529/4885PDE4C 4712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.