SCHEMBL7565859

SCHEMBL7565859

CC(=O)OCCNc1[c]cccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
RECQL P46063 1/20 0.44
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 1/20 0.40
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
THRB P10828 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
RAD52 P43351 1/20 0.35
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
SLC18A3 Q16572 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
PTGS2 P35354 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7802304 0.78 KCNH3 (0.42) KDM4ECYP1A2CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL7795577 0.76 CA12 (0.42) KDM4EKMT2AALDH1A1SMN1; SMN2HSD17B10
SCHEMBL7568911 0.76 TOP2A (0.52) CYP3A4ALDH1A1SMN1; SMN2CYP2C19
SCHEMBL5950512 0.75 KDM4E (0.52) KDM4ERECQLMEN1KMT2ACYP1A2
SCHEMBL6599381 0.75 TDP1 (0.34) KDM4EMEN1KMT2ACYP1A2ALDH1A1
SCHEMBL7795586 0.74 KDM4E (0.33) KDM4EALDH1A1SMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL1066414 0.73 KDM4E (0.51) KDM4ERECQLMEN1KMT2ACYP1A2
SCHEMBL5776915 0.72 RAD52 (0.43) MEN1KMT2ACYP1A2CYP3A4ALDH1A1
SCHEMBL7565863 0.72 KDM4E (0.41) KDM4ERECQLMEN1KMT2ACYP1A2
SCHEMBL1355267 0.72 KDM4E (0.42) KDM4ERECQLMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1234007-A1 OLIGOMERIC METHINE DYES Clariant Finance (BVI) Limited (VG) 2002-08-28 EP disclosed
US-20010012899-A1 Oligomeric methine dyes CLARIANT FINANCE ( BVI) LIMITED 2001-08-09 US disclosed
WO-2001036543-A1 OLIGOMERIC METHINE DYES CLARIANT FINANCE (BVI) LIMITED (VG) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012899-A1 Oligomeric methine dyes INMT, DDT, DDC KDM4E 1276/4885RECQL 462/4885MEN1 718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.