Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565611 | 0.90 | POLB (0.47) | KMT2ANPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL7564957 | 0.82 | MEN1 (0.46) | KMT2AEPHX2HTR1APOLBMEN1 | |
| SCHEMBL8519003 | 0.82 | HTR1A (0.51) | KMT2ANPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL7121410 | 0.80 | KMT2A (0.82) | KMT2ANPC1RAB9APKMEPHX2 | |
| SCHEMBL7129757 | 0.80 | KMT2A (0.82) | KMT2ANPC1RAB9APKMEPHX2 | |
| SCHEMBL7566488 | 0.79 | HTR1A (0.53) | KMT2ANPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL7564124 | 0.79 | POLB (0.60) | KMT2ANPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL7565815 | 0.79 | POLB (0.52) | KMT2ANPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL1101354 | 0.74 | RAB9A (0.60) | KMT2ANPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL7567224 | 0.73 | POLB (0.48) | KMT2ANPC1RAB9ASMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929525-B1 | HETEROARYLOXYETHYLAMINES AS 5-HT1A RECEPTOR LIGANDS | SOD CONSEILS RECH APPLIC (FR) | 2002-09-04 | — | — | EP | claimed |
| EP-0929525-B1 | HETEROARYLOXYETHYLAMINES AS 5-HT1A RECEPTOR LIGANDS | SOD CONSEILS RECH APPLIC (FR) | 2002-09-04 | — | — | EP | disclosed |
| US-6063784-A | HYPOTENSIVE AGENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S. ) (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0929525-A2 | NOVEL HETEROARYLOXYETHYLAMINES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013349-A2 | HETEROARYLOXYETHYLAMINES AS 5-HT1A LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | disclosed |