Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.55 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.53 |
| ▸ | GLRB | P48167 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570866 | 0.87 | NPC1 (0.49) | POLBMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL7565857 | 0.83 | HTR1A (0.48) | KMT2AKDM4EMCHR1HTR1ALMNA | |
| SCHEMBL7566488 | 0.82 | HTR1A (0.53) | POLBMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL7565815 | 0.82 | POLB (0.52) | POLBMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL7573340 | 0.82 | POLB (0.50) | POLBMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL7565853 | 0.81 | MCHR1 (0.48) | KDM4EMCHR1HDAC6RAB9ANPC1 | |
| SCHEMBL7130472 | 0.80 | DRD2 (0.55) | KDM4EHDAC6RAB9AALDH1A1NPC1 | |
| SCHEMBL1101354 | 0.80 | RAB9A (0.60) | POLBMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL7566258 | 0.79 | KMT2A (0.53) | POLBMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL7129424 | 0.79 | NPC1 (0.65) | KDM4EHTR1ARAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929525-B1 | HETEROARYLOXYETHYLAMINES AS 5-HT1A RECEPTOR LIGANDS | SOD CONSEILS RECH APPLIC (FR) | 2002-09-04 | — | — | EP | claimed |
| EP-0929525-A2 | NOVEL HETEROARYLOXYETHYLAMINES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | claimed |
| WO-1998013349-A2 | HETEROARYLOXYETHYLAMINES AS 5-HT1A LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | claimed |
| EP-0929525-B1 | HETEROARYLOXYETHYLAMINES AS 5-HT1A RECEPTOR LIGANDS | SOD CONSEILS RECH APPLIC (FR) | 2002-09-04 | — | — | EP | disclosed |
| US-6063784-A | HYPOTENSIVE AGENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S. ) (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0929525-A2 | NOVEL HETEROARYLOXYETHYLAMINES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013349-A2 | HETEROARYLOXYETHYLAMINES AS 5-HT1A LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | disclosed |