Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566407 | 0.77 | DRD4 (0.42) | DRD4MRGPRX4TDP1REN | |
| SCHEMBL6044046 | 0.76 | REN (0.49) | DRD4REN | |
| SCHEMBL6044054 | 0.76 | REN (0.49) | DRD4REN | |
| SCHEMBL28033822 | 0.71 | TDP1 (0.58) | DRD4TDP1HRH3ALDH1A1CYP1A2 | |
| SCHEMBL2717675 | 0.69 | TDP1 (0.61) | MRGPRX4TDP1HRH3ALDH1A1CYP1A2 | |
| SCHEMBL844653 | 0.68 | ALDH1A1 (0.68) | DRD4TDP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2527684 | 0.68 | ALDH1A1 (0.68) | DRD4TDP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30546900 | 0.68 | ALDH1A1 (0.68) | DRD4TDP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4620895 | 0.68 | ALDH1A1 (0.68) | DRD4TDP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7503285 | 0.67 | SMN1; SMN2 (0.62) | MRGPRX4HRH3CCR1FAAHCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |