Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 12/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044046 | 0.78 | REN (0.49) | DRD4REN | |
| SCHEMBL6044054 | 0.78 | REN (0.49) | DRD4REN | |
| SCHEMBL7566408 | 0.77 | DRD4 (0.42) | DRD4RENTDP1MRGPRX4 | |
| SCHEMBL6042982 | 0.73 | SLC6A2 (0.46) | REN | |
| SCHEMBL3079289 | 0.73 | REN (0.45) | REN | |
| SCHEMBL6041320 | 0.69 | REN (0.48) | REN | |
| SCHEMBL28033822 | 0.69 | TDP1 (0.58) | DRD4TDP1 | |
| SCHEMBL7562291 | 0.68 | ESR1 (0.36) | DRD4 | |
| SCHEMBL30546900 | 0.66 | ALDH1A1 (0.68) | DRD4TDP1 | |
| SCHEMBL844653 | 0.66 | ALDH1A1 (0.68) | DRD4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |