Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 14/20 | 0.58 |
| ▸ | BCHE | P06276 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914704 | 0.94 | ACHE (0.60) | ACHEBCHE | |
| Bromide SCHEMBL29389671 | 0.84 | KDM4E (0.61) | ACHEBCHE | |
| Iodide SCHEMBL17187192 | 0.84 | KDM4E (0.65) | ACHEBCHE | |
| Iodide SCHEMBL10815828 | 0.80 | ACHE (0.66) | ACHEBCHE | |
| Bromide SCHEMBL6865008 | 0.80 | ACHE (0.56) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL6231073 | 0.80 | ACHE (0.67) | ACHEBCHE | |
| SCHEMBL17187153 | 0.80 | ACHE (0.53) | ACHEBCHE | |
| Bromide SCHEMBL17187182 | 0.79 | ACHE (0.55) | ACHEBCHE | |
| SCHEMBL22034130 | 0.78 | ACHE (0.68) | ACHEBCHE | |
| SCHEMBL146423 | 0.78 | ACHE (0.54) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080842-A2 | MEDICAMENT AND METHOD FOR DIAGNOSING AN AUTOIMMUNE CONDITION_IN PARTICULAR PSORIASIS | ESTETECON AB (SE) | 2002-10-17 | — | — | WO | disclosed |