Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737837 | 0.94 | HTR1A (0.54) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL29922564 | 0.91 | HTR2A (0.47) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL577446 | 0.89 | HTR1A (0.57) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL5613920 | 0.89 | HTR2A (0.48) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL29922720 | 0.86 | HTR1A (0.49) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7195698 | 0.86 | HTR1A (0.49) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL27904481 | 0.85 | HTR2A (0.48) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL30666833 | 0.85 | HTR2A (0.48) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL3689438 | 0.83 | HTR1A (0.53) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL32682780 | 0.83 | HTR1A (0.41) | HTR1AHTR2AHTR7DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015462-B1 | BIMETALLIC COMPLEXES AND POLYMERIZATION CATALYSTS THEREFROM | DOW CHEMICAL CO (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6284698-B1 | CATALYST FOR ADDITION POLYMERS | THE DOW CHEMICAL COMPANY | 2001-09-04 | — | — | US | disclosed |
| US-6153776-A | ADDITION POLYMERIZATION CATALYST ACTIVATED BY COCATALYST | THE DOW CHEMICAL (US) | 2000-11-28 | — | — | US | disclosed |
| EP-1015462-A1 | BIMETALLIC COMPLEXES AND POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999014222-A1 | BIMETALLIC COMPLEXES AND POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |