Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737837 | 0.91 | HTR1A (0.54) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL3689438 | 0.89 | HTR1A (0.53) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7566441 | 0.89 | HTR1A (0.53) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL11767791 | 0.87 | HTR1A (0.51) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL3696559 | 0.87 | HTR1A (0.51) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL1539753 | 0.87 | HTR1A (0.51) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL20359652 | 0.87 | HTR1A (0.51) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL1451967 | 0.86 | ACHE (0.51) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL29922720 | 0.84 | HTR1A (0.49) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7195698 | 0.84 | HTR1A (0.49) | HTR1AHTR2AHTR7DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095273-A1 | ALPHA-OLEFIN OLIGOMER AND METHOD FOR PRODUCING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2418228-A1 | A-OLEFIN OLOGIMER AND METHOD FOR PRODUCING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-7910783-B2 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-6673880-B2 | ETHYLENE (CO)POLYMERS HAVING LOW MOLECULAR WEIGHTS AND NARROW MOLECULAR WEIGHT DISTRIBUTIONS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2004-01-06 | — | — | US | disclosed |
| EP-1059299-B1 | Process for the polymerisation of olefins in the presence of indenyl compounds | SABIC POLYPROPYLENES BV (NL) | 2003-12-17 | — | — | EP | disclosed |
| EP-0942011-B1 | Multi-stage process for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-05-14 | — | — | EP | disclosed |
| EP-0849273-B1 | Metallocenes, their preparation and use in the polymerization of alpha-olefins | POLIMERI EUROPA SPA (IT) | 2003-05-02 | — | — | EP | disclosed |
| EP-0941997-B1 | Bridged zirconocene compounds, process for their preparation, and their use as catalyst components in the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-12-18 | — | — | EP | disclosed |
| US-6479609-B1 | Multi-stage process for the polymerization of olefins | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-11-12 | — | — | US | disclosed |
| US-20020039962-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | MONTELL TECHNOLOGY COMPANY B.V. | 2002-04-04 | — | — | US | disclosed |
| US-6342622-B1 | COMPOUNDS HAVING BRIDGING GROUP CONTAINING AT LEAST ONE SP2-HYBRIDISED CARBON ATOM BONDED TO INDENYL GROUP AT 2-POSITION ARE MORE ACTIVE AND/OR GIVE POLYMERS WITH HIGHER MOLECULAR WEIGHT | DSM B.V. (NL) | 2002-01-29 | — | — | US | disclosed |
| US-6306791-B2 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | BASELL TECHNOLOGY COMPANY BV (NL) | 2001-10-23 | — | — | US | disclosed |
| US-20010014751-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymeriaztion of olefins | MONTELL TECHNOLOGY COMPANY B.V. | 2001-08-16 | — | — | US | disclosed |
| US-6262195-B1 | POLYMERIZING ETHYLENE OPTIONALLY WITH ALPHA-OLEFIN IN PRESENCE OF TITANIUM OR VANADIUM COMPOUND CATALYST; CONTACTING PRODUCT WITH COMPOUND TO DEACTIVATE CATALYST, ZIRCOCENE CATALYST AND COCATALYST TO FURTHER POLYMERIZE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-07-17 | — | — | US | disclosed |
| US-6232484-B1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | MONTELL TECHNOLOGY B.V. (NL) | 2001-05-15 | — | — | US | disclosed |
| EP-1059300-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |
| EP-1059299-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |
| EP-0941997-A2 | Bridged zirconocene compounds, process for their preparation, and their use as catalyst components in the polymerization of olefins | Montell Technology Company bv (NL) | 1999-09-15 | — | — | EP | disclosed |
| EP-0942011-A1 | Multi-stage process for the polymerization of olefins | Montell Technology Company bv (NL) | 1999-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | SP1, TTL, TTLL12 | HTR1A 3242/4885HTR2A 4085/4885HTR7 3598/4885 |
| US-20020039962-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | ZRANB2, ZKSCAN2, ZCCHC8 | HTR1A 4039/4885HTR2A 3338/4885HTR7 3497/4885 |
| US-20120095273-A1 | ALPHA-OLEFIN OLIGOMER AND METHOD FOR PRODUCING SAME | OSBP, OXER1, OSBPL8 | HTR1A 3318/4885HTR2A 3733/4885HTR7 2036/4885 |
| US-20010014751-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymeriaztion of olefins | ZRANB2, ZKSCAN2, ZNF787 | HTR1A 3826/4885HTR2A 2539/4885HTR7 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.