Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195698 | 1.00 | HTR1A (0.49) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL5613920 | 0.95 | HTR2A (0.48) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL29922564 | 0.93 | HTR2A (0.47) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL1539753 | 0.89 | HTR1A (0.51) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL737837 | 0.88 | HTR1A (0.54) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7566441 | 0.86 | HTR1A (0.53) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL577446 | 0.84 | HTR1A (0.57) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL8729000 | 0.84 | SIGMAR1 (0.45) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL5064672 | 0.82 | ACHE (0.39) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL28759275 | 0.82 | CYP3A4 (0.40) | HTR1AHTR2AHTR7DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | TERT, MDM4, PCBP1 | HTR1A 2370/4885HTR2A 2519/4885HTR7 3878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.