SCHEMBL756645

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6814968	0.87	SMN1; SMN2 (0.39)	SMN1; SMN2ALDH1A1CYP1A2CYP3A4TSHR
	SCHEMBL16925406	0.84	PLA2G2A (0.36)	SMN1; SMN2MAPTHTTCYP4F2CYP4A11
	SCHEMBL755074	0.79	SMN1; SMN2 (0.36)	SMN1; SMN2ALDH1A1HPGDCYP11B1CYP11B2
	SCHEMBL6810304	0.79	SMN1; SMN2 (0.41)	SMN1; SMN2TSHRHPGDPOLBBRD4
	SCHEMBL13680324	0.65	SMN1; SMN2 (0.40)	SMN1; SMN2ALDH1A1CYP1A2CYP3A4TSHR
	SCHEMBL13850950	0.65	LMNA (0.44)	ALDH1A1TSHRUSP2MAPK1HPGD
	SCHEMBL3845832	0.65	LMNA (0.39)	SMN1; SMN2ALDH1A1CYP1A2CYP3A4TSHR
	SCHEMBL12725710	0.65	SMN1; SMN2 (0.41)	SMN1; SMN2ALDH1A1CYP1A2CYP3A4TSHR
	SCHEMBL755427	0.64	SCN9A (0.34)	ALDH1A1HPGDMAPTHTTMEN1
	SCHEMBL13850959	0.64	MAOB (0.41)	SMN1; SMN2MAPK1POLBLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.