Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.33 |
| ▸ | ITGAV | P06756 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575334 | 0.92 | ITGB3 (0.32) | ITGB3ITGA2BITGAV | |
| SCHEMBL7575967 | 0.91 | SLC6A2 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7566606 | 0.88 | ITGB3 (0.33) | ITGB3ITGA2BITGAV | |
| SCHEMBL7571708 | 0.84 | SLC6A2 (0.32) | ITGB3ITGA2B | |
| SCHEMBL7568240 | 0.79 | SLC6A2 (0.34) | ITGB3ITGA2B | |
| SCHEMBL7007999 | 0.77 | ITGAV (0.52) | ITGB3ITGA2BITGAV | |
| SCHEMBL7006995 | 0.72 | ITGAV (0.45) | ITGB3ITGA2BITGAV | |
| SCHEMBL7012225 | 0.70 | ITGAV (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL7007604 | 0.69 | ITGAV (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL7590655 | 0.66 | ITGAV (0.45) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946165-A4 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0946165-A1 | INTEGRIN ANTAGONISTS | Merck & Co., Inc. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998018460-A1 | INTEGRIN ANTAGONISTS | MERCK & CO., INC. (US) | 1998-05-07 | — | — | WO | disclosed |