Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 17/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.45 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.40 |
| ▸ | ITGB8 | P26012 | 7/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552889 | 1.00 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7592208 | 1.00 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7552205 | 0.90 | ITGAV (0.41) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL7558109 | 0.82 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7571407 | 0.80 | ITGB3 (0.43) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7591261 | 0.78 | ITGAV (0.61) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7589125 | 0.78 | ITGAV (0.61) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7589535 | 0.78 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7563140 | 0.78 | ITGAV (0.37) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL7597028 | 0.78 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB8ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040098-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999031061-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |