Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571708 | 0.92 | SLC6A2 (0.32) | SLC6A2SLC6A3SLC6A4ITGB3ITGA2B | |
| SCHEMBL7566461 | 0.91 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7568240 | 0.89 | SLC6A2 (0.34) | SLC6A2SLC6A3SLC6A4ITGB3ITGA2B | |
| SCHEMBL7566606 | 0.80 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7007604 | 0.79 | ITGAV (0.48) | ITGB3ITGA2B | |
| SCHEMBL7009416 | 0.74 | ITGAV (0.41) | ITGB3ITGA2B | |
| SCHEMBL7589575 | 0.73 | SLC6A2 (0.36) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7013233 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7007999 | 0.69 | ITGAV (0.52) | ITGB3ITGA2B | |
| SCHEMBL7565119 | 0.65 | ROCK2 (0.34) | ITGB3ITGA2BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946165-A4 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | claimed |
| EP-0946165-A1 | INTEGRIN ANTAGONISTS | Merck & Co., Inc. (US) | 1999-10-06 | — | — | EP | claimed |
| WO-1998018460-A1 | INTEGRIN ANTAGONISTS | MERCK & CO., INC. (US) | 1998-05-07 | — | — | WO | claimed |
| EP-0946165-A4 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0946165-A1 | INTEGRIN ANTAGONISTS | Merck & Co., Inc. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998018460-A1 | INTEGRIN ANTAGONISTS | MERCK & CO., INC. (US) | 1998-05-07 | — | — | WO | disclosed |