Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755072 | 0.83 | MAPT (0.43) | MAPTHTR2AGPR3TSHRNPSR1 | |
| SCHEMBL8755331 | 0.67 | HTR2A (0.38) | MAPTHTR2AACHEBCHEGPR3 | |
| SCHEMBL3918548 | 0.67 | HTR2A (0.54) | MAPTHTR2AHTR6MEN1KMT2A | |
| SCHEMBL7602124 | 0.66 | GPR3 (0.46) | HTR2AACHESLC22A2SLC22A3BCHE | |
| SCHEMBL6547416 | 0.66 | GPR3 (0.41) | HTR2AACHESLC22A2SLC22A3BCHE | |
| SCHEMBL796784 | 0.66 | GPR3 (0.41) | HTR2AACHESLC22A2SLC22A3BCHE | |
| SCHEMBL20440936 | 0.66 | GPR3 (0.41) | HTR2AACHESLC22A2SLC22A3BCHE | |
| SCHEMBL21044884 | 0.65 | TSHR (0.39) | HTR2ATSHRCALM1 | |
| SCHEMBL12994236 | 0.64 | GPR3 (0.45) | MAPTSLC22A2SLC22A3HTR6GPR3 | |
| SCHEMBL28586502 | 0.64 | HTR2A (0.35) | MAPTHTR2ASLC22A2SLC22A3GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103315-A1 | Catalyst composition for the polymerization of olefins | PETERSON THOMAS H (US) | 2002-08-01 | — | — | US | disclosed |
| US-20020002256-A1 | CATALYST COMPOSITION FOR THE POLYMERIZATION OF OLEFINS | UNIVATION TECHNOLOGIES, L.L.C. | 2002-01-03 | — | — | US | disclosed |
| EP-1115760-A1 | MONOCYCLOPENTADIENYL METAL CATALYST COMPOSITION FOR THE POLYMERIZATION OF OLEFINS | Univation Technologies LLC (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000015676-A1 | MONOCYCLOPENTADIENYL METAL CATALYST COMPOSITION FOR THE POLYMERIZATION OF OLEFINS | UNIVATION TECHNOLOGIES, LLC (US) | 2000-03-23 | — | — | WO | disclosed |