SCHEMBL7566873

SCHEMBL7566873

O=C(NCC#CI)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.56
LMNA P02545 1/20 0.56
HTT P42858 1/20 0.54
CTSL P07711 4/20 0.51
CTSS P25774 4/20 0.51
CTSB P07858 2/20 0.51
CTSK P43235 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
KEAP1 Q14145 2/20 0.50
NFE2L2 Q16236 2/20 0.50
ALDH1A1 P00352 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MAPT P10636 1/20 0.49
TGM2 P21980 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25014013 0.83 SMN1; SMN2 (0.55) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL1606573 0.82 LMNA (0.61) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL29332369 0.82 SMN1; SMN2 (0.54) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL16834868 0.82 LMNA (0.54) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL9480089 0.81 LMNA (0.50) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL3211861 0.81 LMNA (0.59) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL854096 0.81 CTSS (0.68) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL29332373 0.79 LMNA (0.50) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL137308 0.78 LMNA (0.65) SMN1; SMN2LMNAHTTCTSLCTSS
SCHEMBL13055383 0.78 LMNA (0.80) SMN1; SMN2LMNAHTTL3MBTL1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0438857-B1 Biocidal compositions TROY CHEMICAL CORP (US) 1994-05-04 EP claimed
US-5071479-A Synergistic mixture of iodoalkyk carbamate and tributyltin compound; marine antifouling agent TROY CHEMICAL CORPORATION (US) 1991-12-10 US claimed
EP-0438857-A1 Biocidal compositions TROY CHEMICAL CORPORATION (US) 1991-07-31 EP claimed
WO-2024006517-A1 COPPER CONTAINING COMPOUNDS AND COMPOSITIONS FOR ANTIMICROBIAL PAINT AND COATING Arxada, LLC (US) 2024-01-04 WO disclosed
EP-4025653-B1 STAIN RESISTANT ADDITIVE ARXADA AG (CH) 2023-11-15 EP disclosed
WO-2023187756-A1 IN-PROCESS 'DRYING' FOR OIL BASED TIMBER TREATMENT ARXADA AG (CH) 2023-10-05 WO disclosed
WO-2023101932-A1 COPPER CONTAINING COMPOUNDS AND COMPOSITIONS FOR WET-STATE PAINT AND POLYMER EMULSION PRESERVATION Arxada, LLC (US) 2023-06-08 WO disclosed
EP-4025653-A1 STAIN RESISTANT ADDITIVE Arxada AG (CH) 2022-07-13 EP disclosed
WO-2021067707-A1 STAIN RESISTANT ADDITIVE LONZA SOLUTIONS AG (CH) 2021-04-08 WO disclosed
EP-0670357-B1 Paint film-protective sheet NITTO DENKO CORP (JP) 2002-09-04 EP disclosed
US-5612135-A SUBSTRATE WITH PRESSURE SENSITIVE ADHESIVE LAYER WITH FATTY ACID GLYCEROL ESTER AND FUNGICIDE NITTO DENKO CORPORATION (JP) 1997-03-18 US disclosed
EP-0670357-A1 Paint film-protective sheet NITTO DENKO CORPORATION (JP) 1995-09-06 EP disclosed
EP-0438857-B1 Biocidal compositions TROY CHEMICAL CORP (US) 1994-05-04 EP disclosed
US-5190580-A Antifouling marine paint TROY CHEMICAL CORPORATION (US) 1993-03-02 US disclosed
US-5071479-A Synergistic mixture of iodoalkyk carbamate and tributyltin compound; marine antifouling agent TROY CHEMICAL CORPORATION (US) 1991-12-10 US disclosed
EP-0438857-A1 Biocidal compositions TROY CHEMICAL CORPORATION (US) 1991-07-31 EP disclosed