Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.41 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22892932 | 0.86 | KDR (0.52) | KDRCYP3A4MEN1KMT2ARAB9A | |
| SCHEMBL7531734 | 0.81 | DHODH (0.49) | DHODHEDNRBEDNRARXFP1MAPT | |
| SCHEMBL7532612 | 0.81 | HTT (0.52) | CYP3A4MEN1KMT2ARAB9AMAPT | |
| SCHEMBL7531331 | 0.80 | DHODH (0.55) | DHODHEDNRBEDNRARXFP1CYP3A4 | |
| SCHEMBL7536988 | 0.79 | ACLY (0.50) | CYP3A4MEN1KMT2ARAB9APTPN1 | |
| SCHEMBL7533716 | 0.79 | KDR (0.45) | EDNRBEDNRAKDRCYP3A4MEN1 | |
| SCHEMBL7533616 | 0.78 | MEN1 (0.48) | KDRCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL7537156 | 0.78 | EDNRA (0.51) | DHODHEDNRBEDNRARXFP1KMT2A | |
| SCHEMBL7532056 | 0.77 | SMN1; SMN2 (0.47) | DHODHKDRCYP3A4MEN1KMT2A | |
| SCHEMBL7539041 | 0.74 | MEN1 (0.53) | MEN1KMT2ARAB9AS1PR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |