Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.52 |
| ▸ | FGB | P02675 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EDNRB | P24530 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | NRP1 | O14786 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560628 | 0.90 | LMNA (0.63) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL7569195 | 0.89 | MEN1 (0.49) | MEN1KMT2ANPSR1ACLYSTING1 | |
| SCHEMBL7539025 | 0.89 | MEN1 (0.62) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL7568445 | 0.89 | MEN1 (0.53) | MEN1KMT2AMAPTNPSR1GRM4 | |
| SCHEMBL7531704 | 0.86 | ALDH1A1 (0.57) | MEN1KMT2AMAPTPOLBGRM4 | |
| SCHEMBL7538859 | 0.86 | ACLY (0.53) | DHODHMEN1KMT2ANPSR1ACLY | |
| SCHEMBL7539041 | 0.86 | MEN1 (0.53) | MEN1KMT2APOLBGRM4ACLY | |
| SCHEMBL7537156 | 0.85 | EDNRA (0.51) | DHODHKMT2AEDNRBEDNRAACLY | |
| SCHEMBL7534407 | 0.84 | LMNA (0.56) | MEN1KMT2AMAPTGRM4ACLY | |
| SCHEMBL7533710 | 0.84 | CYP3A4 (0.70) | MEN1KMT2AMAPTPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |