SCHEMBL7566982

SCHEMBL7566982

O=C(CO)Oc1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
ELANE P08246 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
LIPE Q05469 2/20 0.43
HPGD P15428 2/20 0.42
POLB P06746 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
RAB9A P51151 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931453 0.89 KMT2A (0.54) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL643983 0.84 KMT2A (0.63) KMT2ATDP1MAPTALDH1A1LMNA
SCHEMBL1244295 0.84 KMT2A (0.54) KMT2ATDP1MAPTALDH1A1LMNA
SCHEMBL4673743 0.83 KMT2A (0.71) KMT2AMAPTLMNAPOLB
SCHEMBL10768902 0.83 KMT2A (0.49) KMT2ATDP1MAPTALDH1A1LMNA
SCHEMBL11717993 0.83 KMT2A (0.49) KMT2ATDP1MAPTALDH1A1LMNA
SCHEMBL10502576 0.81 KMT2A (0.61) KMT2ATDP1MAPTALDH1A1LMNA
SCHEMBL11804399 0.81 KMT2A (0.60) KMT2ATDP1MAPTALDH1A1LMNA
SCHEMBL2927179 0.81 KMT2A (0.47) KMT2ATDP1MAPTALDH1A1LMNA
SCHEMBL197418 0.81 KMT2A (0.63) KMT2ATDP1MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101019541-B Composite prepn for increasing tomato yield UNIV SHENYANG AGRICULTURAL 2010-06-16 CN disclosed
CN-100508751-C Beta cyclodextrin parachlorophenoxy acetic acid solid inclusion compound and preparation and application thereof UNIV NORTHWEST NORMAL (CN) 2009-07-08 CN disclosed
CN-101019541-A Composite prepn for increasing tomato yield UNIV SHENYANG AGRICULTURAL (CN) 2007-08-22 CN disclosed
CN-1802918-A Plant growth regulation ROHM & HAAS (US) 2006-07-19 CN disclosed
CN-1685815-A Beta cyclodextrin parachlorophenoxy acetic acid solid inclusion compound and its preparation and application XIBEI NORMAL UNIV (CN) 2005-10-26 CN disclosed
EP-0746551-B1 OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS UNIV OHIO STATE RES FOUND (US) 2002-09-04 EP disclosed
EP-0746551-A1 OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-12-11 EP disclosed
US-5504108-A ANTIAGGLOMERANTS, ANTIARTHRITIC AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-04-02 US disclosed
WO-1995023139-A1 OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-08-31 WO disclosed
US-5399721-A Anticoagulant; prepared from aldehyde THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-03-21 US disclosed
US-4052212-A ETHER-ESTER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-10-04 US disclosed