Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.53 |
| ▸ | ACE | P12821 | 8/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447079 | 0.95 | MME (0.46) | MMEACEPPARGPPARACTSB | |
| SCHEMBL7567698 | 0.92 | MME (0.59) | MMEACECTSB | |
| SCHEMBL7568168 | 0.89 | MME (0.60) | MMEACEPPARGPPARAMEN1 | |
| SCHEMBL7567838 | 0.89 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7568360 | 0.89 | MME (0.66) | MMEACECTSB | |
| SCHEMBL27463258 | 0.89 | MME (0.64) | MMEACEPPARGPPARAMEN1 | |
| SCHEMBL8030383 | 0.89 | MME (0.64) | MMEACEPPARGPPARAMEN1 | |
| SCHEMBL7567320 | 0.88 | MME (0.66) | MMEACECTSB | |
| SCHEMBL8447081 | 0.87 | PPARG (0.42) | MMEACEPPARGPPARACTSB | |
| SCHEMBL8446430 | 0.87 | MME (0.52) | MMEACECTSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |