Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.66 |
| ▸ | ACE | P12821 | 8/20 | 0.66 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449475 | 0.95 | MME (0.60) | MMEACEHRH4TACR1CPA1 | |
| SCHEMBL7567288 | 0.88 | MME (0.53) | MMEACECTSB | |
| SCHEMBL8027391 | 0.88 | MME (0.80) | MMEACEHRH4TACR1CPA1 | |
| SCHEMBL27446785 | 0.88 | MME (0.80) | MMEACEHRH4TACR1CPA1 | |
| SCHEMBL7568978 | 0.87 | MME (0.78) | MMEACEHRH4CPA1ACE2 | |
| SCHEMBL7567634 | 0.87 | MME (0.49) | MMEACECTSBCASP1 | |
| SCHEMBL7574571 | 0.86 | MME (0.49) | MMEACECTSBCASP1 | |
| SCHEMBL7574270 | 0.85 | MME (0.70) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL7574618 | 0.85 | MME (0.55) | MMEACECPA1ACE2CTSB | |
| SCHEMBL7574613 | 0.85 | MME (0.55) | MMEACECPA1ACE2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |