Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.49 |
| ▸ | ACE | P12821 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568871 | 0.89 | MME (0.55) | MMEACEMEN1KMT2ALPAR1 | |
| SCHEMBL7567634 | 0.89 | MME (0.49) | MMEACEMEN1KMT2ACTSB | |
| SCHEMBL7567320 | 0.86 | MME (0.66) | MMEACECTSBCASP1 | |
| SCHEMBL7574270 | 0.82 | MME (0.70) | MMEACECTSBCASP1 | |
| SCHEMBL8449475 | 0.81 | MME (0.60) | MMEACECTSBCASP1 | |
| SCHEMBL7567288 | 0.81 | MME (0.53) | MMEACEMEN1KMT2ACTSB | |
| SCHEMBL8446444 | 0.81 | KMT2A (0.41) | MEN1KMT2ACTSBCASP1 | |
| SCHEMBL7567838 | 0.80 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7568360 | 0.80 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7567870 | 0.79 | MME (0.61) | MMEACECTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |