Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipentylamine SCHEMBL7568173 | 0.93 | ALDH1A1 (0.62) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL28881979 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL6392617 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL28881970 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Dipentylamine SCHEMBL3469134 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL6390465 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL7562435 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL7567094 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL7562827 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Nitric Acid SCHEMBL28881965 | 0.91 | ALDH1A1 (0.59) | ALDH1A1TSHRADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020016505-A1 | Heat storage material having solid/solid phase transition remains solid through application; heat resistance; materials handling | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | US | claimed |
| CN-1321720-A | Storage medium of latent heat storage system | MERCK PATENT GMBH (DE) | 2001-11-14 | — | — | CN | claimed |
| EP-1148108-A1 | Storage media for latent heat storage units | MERCK PATENT GmbH (DE) | 2001-10-24 | — | — | EP | claimed |
| CN-115494167-A | Method for realizing co-outflow of phosphorothioate oligonucleotide isomers in chromatographic analysis | 南京金斯瑞生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-113471424-B | Ternary cathode material of lithium ion battery and preparation method thereof | 青海师范大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113471424-A | Ternary cathode material of lithium ion battery and preparation method thereof | 青海师范大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-102303879-B | Method for preparing magnesium hydroxide by utilizing light calcined dolomite | WUHAN INST TECHNOLOGY | 2013-06-19 | — | — | CN | disclosed |
| CN-102351221-B | Method for preparing magnesium hydroxide from acid-dissolved magnesium ion-containing raw materials | WUHAN INST TECHNOLOGY | 2013-05-01 | — | — | CN | disclosed |
| CN-102275958-B | Method for preparing magnesium hydroxide utilizing magnesium sulfate as raw material | WUHAN INST TECHNOLOGY | 2013-02-06 | — | — | CN | disclosed |
| CN-102351221-A | Method for preparing magnesium hydroxide from acid-dissolved magnesium ion-containing raw materials | WUHAN INST TECHNOLOGY | 2012-02-15 | — | — | CN | disclosed |
| CN-102303879-A | Method for preparing magnesium hydroxide by utilizing light calcined dolomite | WUHAN INST TECHNOLOGY | 2012-01-04 | — | — | CN | disclosed |
| CN-102275958-A | Method for preparing magnesium hydroxide utilizing magnesium sulfate as raw material | — | 2011-12-14 | — | — | CN | disclosed |
| CN-201664447-U | Disposable air purification infusion apparatus | ZIXIANG PAN | 2010-12-08 | — | — | CN | disclosed |
| US-20020033247-A1 | Use of PCMs in heat sinks for electronic components | MERCK PATENT GMBH (DE) | 2002-03-21 | — | — | US | disclosed |
| US-20020016505-A1 | Heat storage material having solid/solid phase transition remains solid through application; heat resistance; materials handling | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | US | disclosed |
| CN-1329361-A | Application of phase transformation material in radiator for electronic element and device | MERCK PATENT GMBH (DE) | 2002-01-02 | — | — | CN | disclosed |
| EP-1162659-A2 | Use of PCM in heat sinks for electronic devices | MERCK PATENT GmbH (DE) | 2001-12-12 | — | — | EP | disclosed |
| CN-1321720-A | Storage medium of latent heat storage system | MERCK PATENT GMBH (DE) | 2001-11-14 | — | — | CN | disclosed |
| EP-1148108-A1 | Storage media for latent heat storage units | MERCK PATENT GmbH (DE) | 2001-10-24 | — | — | EP | disclosed |
| US-4732705-A | ION EXCHANGE RESIN SOLIDIFIED WITH CEMENT | GESELLSCHAFT ZUR FORDERUNG DER INDUSTRIEORIENTIERTEN FORSCHUNG AN DEN SCHWEIZERISCHEN HOCHSCHULEN UND WEITEREN INSTITUTIONEN (CH) | 1988-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016505-A1 | Heat storage material having solid/solid phase transition remains solid through application; heat resistance; materials handling | HSPH1, HSP90AA1, HSPA1A | ALDH1A1 1431/4885TSHR 4373/4885ADH1B 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.