Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 6/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567377 | 0.85 | AOX1 (0.58) | AOX1HDAC1HDAC6RAD52SMARCA2 | |
| SCHEMBL8413595 | 0.85 | AOX1 (0.54) | AOX1HDAC1HDAC6RAD52SMARCA2 | |
| SCHEMBL7567367 | 0.85 | AOX1 (0.56) | AOX1HDAC1HDAC6RAD52SMARCA2 | |
| SCHEMBL7567208 | 0.80 | HDAC1 (0.43) | AOX1HDAC1HDAC6RAD52HTT | |
| SCHEMBL7565052 | 0.77 | RAD52 (0.46) | AOX1HDAC1HDAC6RAD52KCNH2 | |
| SCHEMBL7568123 | 0.76 | RAD52 (0.47) | AOX1HDAC1HDAC6RAD52SMARCA2 | |
| SCHEMBL7567233 | 0.76 | RAD52 (0.40) | HDAC1HDAC6RAD52UHRF1HTT | |
| SCHEMBL7568141 | 0.74 | RAD52 (0.52) | HDAC1HDAC6RAD52UHRF1HTT | |
| SCHEMBL7564176 | 0.74 | AOX1 (0.56) | AOX1HDAC1HDAC6RAD52SMARCA2 | |
| SCHEMBL7566347 | 0.74 | HDAC1 (0.67) | AOX1HDAC1HDAC6RAD52SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |