Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CASP1 | P29466 | 6/20 | 0.38 |
| ▸ | CASP7 | P55210 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565052 | 0.93 | RAD52 (0.46) | RAD52TP53RAB9ANPC1KDM4E | |
| SCHEMBL7567233 | 0.91 | RAD52 (0.40) | RAD52KDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL8413334 | 0.86 | RAD52 (0.54) | RAD52TP53RAB9ANPC1KDM4E | |
| SCHEMBL7567419 | 0.84 | RAD52 (0.60) | RAD52TP53MAPTHTTUHRF1 | |
| SCHEMBL7567208 | 0.84 | HDAC1 (0.43) | RAD52KDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL7565057 | 0.78 | RAD52 (0.54) | RAD52TP53HTTHDAC1HDAC6 | |
| SCHEMBL7568123 | 0.76 | RAD52 (0.47) | RAD52KDM4EATMHPGDGAA | |
| SCHEMBL7567029 | 0.76 | RAD52 (0.45) | RAD52RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL8415109 | 0.76 | RAD52 (0.47) | RAD52KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL7567238 | 0.74 | RAD52 (0.47) | RAD52TP53MAPTPIK3CDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |